Table 4. Classification by Treatment Results and Adverse Event

Case study
No. Results (Baseline → ET) AE
Hwang EH11) 1. VAS(Rt, Lt): (6, 4) → (3,3)2. THI(functional, emotional, catastrophic, total): Baseline (34, 16, 4, 54) → 1 wk after Tr (26, 12, 4, 42) → ET (22, 8, 4, 34)
Zhang LL12) 1. TEQ: 14 → 42. THI: 47 → 143. F/U after 6 months: Condition is maintained as at the end of treatment.
Yang WW13) 1. THI: 48.38±25.45 → 36.31±21.112. TEQ: 13.28±4.19 → 10.56±3.613. SRSS: 27.88±7.84 → 24.13±6.414. SAS: 38.63±8.53 → 35.06±7.41*5. SDS: 39.63±12.34 → 36.38±11.15*6. Total effective rate: 71.9% mild subcutaneous hematoma (6 patients)- resolved spontaneously.
Nie JT14) 1. Effective rate: 痊愈(13.9%), 有效(25.0%), 显效(52.8%), 无效(8.3%) 1-1. Total effective rate: 91.7%2. F/U after 6 months(1 case): No recurrence.
Ho LF15) 1. NRS (Baseline → ET → F/U after 5 weeks)Gr(EA): 6.33±0.28 → 4.76±0.32‡∥ → 4.80±0.34‡∥Gr(EA+WA): 6.48±0.28 → 4.86±0.32‡∥ → 4.85±0.34‡∥Gr(WL): 6.56±0.28 → 6.68±0.32 → 6.83±0.342. THI (Baseline → ET → F/U after 5 weeks)2-1. Functional: Gr(EA)(20.80±1.92→15.40±1.98‡§→15.13±2.00‡§), Gr(EA+WA)(18.00±1.92→12.46±1.98‡∥→12.40±2.00‡∥), Gr(WL)(20.33±1.92→23.86±1.98→25.20±2.00)2-2. Emotional: Gr(EA)(14.33±1.51→9.73±1.45‡§→9.06±1.47‡∥), Gr(EA+WA)(13.00±1.51→8.80±1.45†∥→8.60±1.47†∥), Gr(WL)(14.26±1.51→16.26±1.45→17.20±1.47)2-3. Catastrophic: Gr(EA)(11.33±0.83→10.40±0.83§→10.26±0.86§), Gr(EA+WA)(9.13±0.83→9.00±0.83§→9.13±0.86§), Gr(WL)(11.53±0.83→13.06±0.83→13.46±0.86)2-4. Total: Gr(EA)(46.46±3.86→35.53±3.94‡§→34.46±4.02‡∥), Gr(EA+WA)(40.13±3.86→30.26±3.94†∥→30.13±4.02†∥), Gr(WL)(46.13±3.86→53.20±3.94→55.86±4.02) Gr(EA): Pain at the treatment site(1), bruising at the treated site(3)Gr(EA+WA): Pain at the treatment site(1), bruising at the treated site(2)- all minor and naturally resolved(except 1 patient(Gr(EA)) dropout due to pain at the treated site).
Lu ZQ16) 1. Total effective rate(Gr(WA+Chuna), Gr(WM)): (87.5%, 63.3%)
Gao JL17) 1. THI(Gr(EA), Gr(WA)): (35.23±5.98→20.18±4.15*, 35.78±6.37→18.76±3.37*)2. Hamilton depression rating scale(Gr(EA), Gr(WA)): (14.07±2.71→6.68±0.57*, 13.64±3.22→6.07±0.96*)3. 耳鸣严重程度评分(Gr(EA), Gr(WA)): (14.01±2.13→6.78±0.81*, 13.79±2.21→6.61±0.76*)4. Total effective rate(Gr(EA), Gr(WA)): (91.18%, 92.65%)
Luo JM18) 1. VAS(Gr(WA), Gr(Acu)): (5.53±1.38→2.53±1.50*, 5.17±1.49, 3.37±1.38*)2. Tinnitus severity score(Gr(Acu), Gr(WA)): (14.93±3.06→6.97±5.10*, 14.87±3.74→9.90±5.3*)3. NPQ(Gr(Acu), Gr(WA)): (21.13±4.46→11.00±4.67*, 21.30±6.70→15.53±4.61*)4. Total effective rate(Gr(Acu), Gr(WA)): (86.67%, 76.67%)
ET: End of treatment, AE: Adverse event, VAS: Visual analogue scale, THI: Tinnitus handicap inventory, Rt: Right, Lt: Left, wk: week, Tr: treatment, TEQ: Tinnitus evaluation questionnaire, SRSS: Self-rating scale of sleep, SAS: Self-rating anxiety scale, SDS: Self-rating depression scale, F/U: Follow-up, NRS: Numeral rating scale, NPQ: Northwick Park Neck Pain Scale
compared with baseline, <0.05; †, <0.01; ‡, <0.001; compared with Gr(WL) §, <0.05; ∥, <0.001, compared with Gr(Acu) ¶, <0.05