| Shi11) (2018) | C : 36 | 1. Prednisone Acetate2. Gennadol + 5% D/W3. Vestibular Rehabilitation Exercise | 1. 15 days2. 14 days3. 1 month4. 21 days | 1. Spontaneous Nystagmus Measurement2. DHI‡ ① DHI-P ② DHI-F ③ DHI-E ④ Total-DHI3. VEMPs§ Abnormal Cases ① cVEMPs∥ ② oVEMPs¶4. vHIT** Abnormal Cases ① Horizontal Semicircular Canal ② Anterior Semicircular Canal ③ Posterior Semicircular Canal5. Total Effective Rate | 1. T>C(p<0.05) C : 7.17±2.23 → 4.31±1.04 T : 7.21±2.05 → 2.08±0.632. T>C(p<0.05) ① C : 15.34±1.82 → 3.00±1.02 T : 15.67±1.63 → 2.16±0.7 ② C : 13.87±1.59 → 4.42±0.93 T : 13.67±1.45 → 1.92±0.88 ③ C : 14.45±1.81 → 3.92±1.02 T : 14.23±1.77 → 2.12±0.98 ④ C : 43.66±2.97 → 11.32±1.74 T : 43.33±2.55 → 6.20±1.693. T>C(p>0.05) ① C : 14(38.89%) → 12(33.33%) T : 12(33.33%) → 9(25%) ② C : 32(88.89%) → 28(77.78%) T : 33(91.67%) → 25(69.44%)4. T>C(p>0.05) ① C : 32(88.89%) → 27(75%) T : 33(91.67%) → 25(69.44%) ② C : 32(88.89%) → 27(75%) T : 33(91.67%) → 25(69.44%) ③ C : 14(38.89%) → 12(33.33%) T : 12(33.33%) → 9(25%)5. T>C(p<0.05) C : 25(69.44%) T : 33(91.67%) | NR‡ |
| T : 36 | 1. Prednisone Acetate2. Gennadol + 5% D/W3. Vestibular Rehabilitation Exercise4. Sangguk-eum |
| Wu12) (2021) | C : 18 | 1. Methylprednisolone2. Methylcobalamin | 1. 6 days2. 14 days3. 14 days | 1. Total-DHI2. VADL‡3. BBS‡4. CP‡ Value ① CP Value ② CP Value Difference5. VOR‡ Gain Value6. Treatment Effect ① Total Effective Rate ② Significant Effective Rate | 1. T>C(p<0.05) C : 69.89±18.38 → 29.44±11.23 T : 76.40±11.47 → 22.60±7.112. T>C(p<0.05) C : 179.11±59.82 → 75.06±17.05 T : 206.25±44.73 → 61.95±13.803. T>C(p<0.05) C : 20.44±14.32 → 40.78±9.11 T : 13.35±11.82 → 45.95±4.50 4. T>C(p<0.05) ① C : 66.67±24.12 → 48.56±16.71 T : 71.20±21.08 → 41.30±8.83T>C(p<0.05) ② C : 18.11±14.55 T : 29.90±19.315. T>C(p<0.05) C : 46.50±14.36 → 70.28±6.89 T : 51.10±14.84 → 74.35±5.226. T>C(p>0.05) ① C : 94% T : 95%T>C(p<0.05) ② C : 17% T : 60% | NR |
| T : 20 | 1. Methylprednisolone2. Methylcobalamin3. Jeonghyeon-granule II |
| Sun13) (2021) | C : 35 | 1. Gastrodin + 5% D/W2. Oxiracetam3. Prednisone Acetate4. Pantoprazole Sodium5. Calcium Carbonate D36. Vestibular Rehabilitation Exercise | 1. 14 days2. 14 days3. 3 days4. 14 days5. 14 days6. 14 days7. 14 days | 1. DHI ① DHI-P ② DHI-F ③ DHI-E ④ Total-DHI2. VSI‡ ① Headache ② Nausea ③ Dizziness ④ Vertigo ⑤ Balance ⑥ Visually Sensitive3. CP Value (normal value≤20)4. vHIT ① Compensatory Eye Movement ② Regression Gain Value (normal value≥0.9) ③ Regression Gain Asymmetry Value Ratio (≤12%) | 1. T>C(p<0.05) ① C : 20.63±3.75 → 15.20±3.15 T : 21.21±3.94 → 14.67±3.52 ② C : 29.77±4.19 → 20.40±4.47 T : 30.79±4.06 → 19.09±2.70 ③ C : 24.69±5.82 → 17.89±4.14 T : 23.33±6.26 → 15.64±4.76 ④ C : 75.09±8.95 → 53.49±6.99 T : 75.33±8.38 → 49.39±6.492. T>C(p<0.05) ① C : 2.37±1.63 → 1.46±1.44 T : 2.15±1.50 → 1.21±1.22 ② C : 5.37±1.77 → 2.54±1.46 T : 5.70±2.26 → 2.24±1.37 ③ C : 6.83±2.18 → 3.60±2.12 T : 5.88±2.60 → 2.00±1.46 ④ C : 5.63±2.06 → 3.06±1.88 T : 5.45±1.99 → 1.82±1.45 ⑤ C : 6.89±1.59 → 3.34±1.31T : 7.12±1.36 → 2.73±1.33 ⑥ C : 3.57±1.75 → 2.06±1.45 T : 3.24±1.32 → 1.24±1.173. T>C(p<0.05) C : 68.20±4.46 → 17.54±2.29 T : 67.15±5.66 → 14.46±3.014. T>C(p<0.05) ① C : 29(83.00) → 19(54.00) T : 27(82.00) → 15(45.00) ② C : 17(49.00) → 21(60.00) T : 15(45.00) → 25(76.00) ③ C : 16(46.00) → 20(57.00) T : 14(42.00) → 24(73.00) | NR |
| T : 33 | 1. Gastrodin + 5% D/W2. Oxiracetam3. Prednisone Acetate4. Pantoprazole Sodium5. Calcium Carbonate D36. Vestibular Rehabilitation7. gami-Sanggug-eum |
| Sun14) (2021) | C : 25 | 1. Gastrodin + 5% D/W2. Oxiracetam + 5% D/W3. Methylprednisolone4. Pantoprazole Sodium5. Calcium Carbonate D36. Vestibular Rehabilitation Exercise | 1. 14 days2. 14 days3. 3 days4. 14 days5. 14 days6. 14 days7. 14 days | 1. VSI ① Balance ② Vertigo ③ Dizziness ④ Nausea ⑤ Visually Sensitive ⑥ Headache2. CP Value3. vHIT ① Horizontal Semicircular Canal 1 Compensatory Eye Movement 2 60ms Instantaneous Value (normal value≥0.8) 3 Regression Gain Value (normal value≥0.9) 4 Regression Gain Asymmetry Value Ratio (≤14%) ② Semicircular Canal 1 Compensatory Eye Movement 2 Regression Gain Value (normal value≥0.9) 3 Regression Gain Asymmetry Value Ratio (≤14%) | 1. T>C(p<0.05) ① C : 7.16±0.62 → 3.84±0.74 T : 7.36±0.70 → 1.36±0.63 ② C : 6.96±0.67 → 3.72±1.02 T : 7.20±0.76 → 2.04±0.84 ③ C : 6.56±0.71 → 3.72±1.24 T : 6.88±0.83 → 1.68±0.90 ④ C : 6.64±0.70 → 3.04±0.61 T : 7.04±0.93 → 1.04±0.67 ⑤ C : 6.92±0.70 → 3.64±0.86 T : 6.96±0.73 → 1.24±0.83 ⑥ C : 6.44±0.58 → 3.20±0.76 T : 6.44±0.58 → 1.04±0.882. T>C(p<0.05) C : 65.76±3.76 → 18.52±1.44 T : 67.24±4.91 → 13.80±1.603. T>C(p<0.05) ① 1 C : 23(80.00) → 16(64.00) T : 22(88.00) → 13(52.00) 2 C : 16(64.00) → 14(56.00) T : 20(80.00) → 11(44.00) 3 C : 19(76.00) → 13(52.00) T : 23(92.00) → 10(40.00) 4 C : 22(88.00) → 11(44.00) T : 21(84.00) → 8(32.00) ② 1 C : 21(84.00) → 14(56.00) T : 23(92.00) → 12(48.00) 2 C : 22(88.00) → 12(48.00) T : 22(88.00) → 13(52.00) 3 C : 21(84.00) → 15(60.00) T : 19(76.00) → 11(44.00) | NR |
| T : 25 | 1. Gastrodin + 5% D/W2. Oxiracetam + 5% D/W3. Methylprednisolone4. Pantoprazole Sodium5. Calcium Carbonate D36. Vestibular Rehabilitation Exercise7. Sanggug-eum-gagam |
| Zhou15) (2022) | C : 56 | 1. Micro Circulation Improvement Drug | 1. 14 days2. 14 days | 1. Total Effective Rate2. DHI ① DHI-E ② DHI-F ③ DHI-P ④ Total-DHI3. VEST‡4. SOT‡5. Serum Inflammatory Factor Levels ① TNF-α‡ ② IL-6‡ | 1. T>C(p<0.05) C : 76.79% T : 92.86%2. T>C(p<0.05) ① C : 24.89±3.52 → 17.38±2.35 T : 25.47±3.41 → 12.34±2.78 ② C : 27.96±2.45 → 22.98 3.21 T : 28.53±2.31 → 17.20±2.76 ③ C : 24.76±2.24 → 19.90±2.89 T : 25.21±2.57 → 15.65±3.12 ④ C : 77.65±4.56 → 60.26±3.86 T : 79.23±5.25 → 45.19±4.213. T>C(p<0.05) C : 18.34±7.21 → 43.24±8.29 T : 17.68±5.48 → 60.93±7.894. T>C(p<0.05) C : 50.89±6.62 → 62.34±6.13 T : 51.43±5.45 → 76.58±4.975. T>C(p<0.05) ① C : 18.52±1.78 → 15.78±1.45 T : 18.43±1.42 → 13.56±1.29 ② C : 24.89±3.41 → 19.90±3.67 T : 25.41±3.28 → 14.35±2.76 | C : 0%T : 0% |
| T : 56 | 1. Micro Circulation Improvement Drug2. Sopungcheongyeolhwalhyeol-bang |
| Wang16) (2022) | C : 45 | 1. Betahistine Mesilate2. Prednisone | 1. 14 days2. 7 days3. 14 days | 1. Total Effective Rate2. Chinese Medicine Symptom Score ① Dizziness Vertigo ② Feeling Of Head Heaviness ③ Chest Fullness and Stuffiness ④ Fatigue3. Total-DHI4. Chinese Medicine Syndrome Score5. CP Value 6. vHIT ① Horizontal Semicircular Canal Gain Value ② Anterior Semicircular Canal Gain Value ③ Posterior Semicircular Canal Gain Value 7. IL-68. NLR‡9. PLR‡ | 1. T>C(p<0.05) C : 34(75.56%) T : 42(91.30%)2. T>C(p<0.05) ① C : 2.61±0.26 → 1.42±0.48 T : 2.67±0.23 → 0.95±0.12 ② C : 2.57±0.22 → 1.51±0.52 T : 2.62±0.19 → 0.93±0.34 ③ C : 2.51±0.18 → 1.23±0.44 T : 2.57±0.25 → 0.86±0.42 ④ C : 2.47±0.21 → 1.12±0.46 T : 2.58±0.26 → 0.75±0.313. T>C(p<0.05) C : 65.23±23.32 → 16.73±13.67 T ; 66.77±22.98 → 9.89±11.414. T>C(p<0.05) C : 24.92±5.31 → 15.69±3.25 T : 25.56±4.63 → 10.31±2.625. T>C(p<0.05) C : 66.34±4.23 → 20.26±6.37 T ; 67.76±5.03 → 14.32±5.316. T>C(p<0.05) ① C : 0.52±0.12 → 0.57±0.46 T : 0.51±0.25 → 0.65±0.16 ② C : 0.50±0.51 → 0.56±0.23 T : 0.50±0.23 → 0.61±0.37 ③ C : 0.49±0.35 → 0.55±0.12 T : 0.49±0.13 → 0.59±0.137. T>C(p<0.05) C : 27.74±0.88 → 16.52±0.73 T : 28.37±0.62 → 10.11±1.07 8. T>C(p<0.05) C : 2.48±0.36 → 1.86±0.38 T : 2.52±0.24 → 1.53±0.439. T>C(p<0.05) C : 123.34±5.03 → 112.52±4.93 T : 124.47±4.62 → 101.03±5.51 | NR |
| T : 46 | 1. Betahistine Mesilate2. Prednisone3. Jeonghyeon-tang |
| Li17) (2024) | C : 30 | 1. Vitamin B12. Methylcobalamin3. Prednisone Acetate4. Betahistine | 1. 14 days2. 14 days3. 5 days4. 14 days5. 14 days | 1. NLR2. PLR3. CRP‡4. Total-DHI5. CP Value6. vHIT ① Compensatory Eye Movement ② Regression Gain Value≥0.9 ③ Regression Gain Asymmetry Value Ratio≤12% | 1. T>C(p<0.05) C : 9.28±2.12 → 2.11±0.87 T : 9.24±2.32 → 1.12±0.63 2. T>C(p<0.05) C : 230.14±23.57 → 145.75±12.64 T : 228.94±29.62 → 92.54±28.463. T>C(p<0.05) C : 28.42±5.64 → 5.08±2.35 T : 28.66±5.87 → 2.84±1.234. T>C(p<0.05) C : 23.44±7.17 → 16.53±6.25 T : 22.92±6.63 → 12.31±5.465. T>C(p<0.05) C : 35.41±5.03 → 21.23±4.55 T : 35.34±4.12 → 15.24±4.116. T>C(p<0.05) ① C : 25(83.33) → 16(53.33) T : 24(80.00) → 13(43.33) ② C : 15(50.00) → 23(76.67) T : 14(46.66) → 25(83.33) ③ C : 14(46.67) → 22(73.33) T : 13(43.33) → 24(80.00) | NR |
| T :30 | 1. Vitamin B12. Methylcobalamin3. Prednisone Acetate4. Betahistine5. Sihocheongsang-tang |