Table 1. Characteristics of Clinical Studies of Oriental Medicine on Rosacea

First Author (year)	Rosacea Type	Treatment intervention		Control Intervention	Treatment Period	Result
		Herbal Medicine	Acupuncture Treatment
Case report
Kim29)(2022)	Erythemato-Telangiectatic type	Sosiho-tang(120ml PO TID)Oryeong-san(120ml PO TID)	Duration 20min, QDAcupoint (BL2, CV24, TE17, TE23, GB1, SI18, ST3, ST6, ST7, GV26, LI4, ST36)Electroacupuncture (TE23-GB1, ST6-ST7, 1Hz)	NA	76Days	1. VAS 9 → 02. DLQI 22 → 0
Lee28) (2020)	Erythemato-Telangiectatic type	Baekho-tang(120ml PO TID)	NA	NA	15Days	1. RSEI 8 → 0
Kang30) (2019)	Erythemato-Telangiectatic type	Yangdokbaekho-tang(120ml PO TID)Hwangryunhaedok-Tang(120ml WD BID Duration 15min)	Duration 10-15min, BIDAcupoint (SI18, ST2, GB3, ST7, LI4, ST36, SP6)	NA	12Days	1. HFS 20 → 62. NRS 7 → 1
Gao31) (2018)	Erythemato-Telangiectatic type	NA	Duration 45min, 3times/weekAcupoint (EX-HN3, EX-HN5, LI20, CV24)Hand manipulation (lifting and thrusting, twirling and rotating / repeated 3 times every 15min)	NA	1week	1. DLQI 15 → 02. LD 151 units→ 129 units
Retrospective Cohort study
Mao27) (2020)	NR	B(n=55) : Rose Yurong Decoction (PO BID) + WD	NA	A(n=54) : WD (Doxycycline Hyclate, 100mg PO QD + Hydroxychloroquine tablet, 100mg PO BID)	8weeks	1. SLS B<A (p<0.05)2. SRS B<A (p<0.05)3. CE A(75.93%) < B(96.36%) (p<0.05)4. SH,SE,HCA<B(p<0.05)5. AE A(11.11%) < B(12.73%) (p>0.05)6. RR B(3.64%) < A(29.63%) (p<0.05)

NA : Not applicable, NR : Not reported, PO: Per OS, WD: Wet dressing, QD: Quaque die, BID: Bis in die, TID: Ter in die, RSEI: Rosacea Symptom Evaluation Index, NRS : Numeral Rating Scale, HFS: Hot Flush Score, LD: Laser Doppler, WD : Western medicine, SLS: Skin lesion score, SRS: Self-reported score, CE: Clinical efficiency, SH: Skin hydration, SE: Skin elasticity, HC: Hemoglobin content, AE: Adverse effect, RR: Recurrence rate, VAS : Visual Analogue Scale, DLQI : Dermatology Life Quality Index