| Yin10) (2007) | C : 30 | Amoxicillin | 5 days | 1. TER2. Onset of Effect3. Recovery Time | 1. T>C(p<0.05) C : 86.7% T : 94%2. T>C(p<0.05) C : (3.48±0.58)h T : (1.52±0.71)h3. T>C(p>0.05) C : (4.5±2.07)d T : (4.13±1.31)d | NR |
| T : 100 | Cheongin-tang |
| Pan11) (2010) | C : 60 | Cefuroxime Axetil | 3 days | 1. TER | 1. T>C(p=0.036, p<0.05) C : 80.0% T : 95.0% | NR |
| T : 60 | Yukmi-tang |
| Liu12) (2012) | C : 35 | Cephalexin Capsule | 10 days | 1. TER | 1. T>C(p=0.036, p<0.05) C : 68.6% T : 97.1% | NR |
| T : 68 | Yukmi-tang |
| Jang13) (2012) | C : 45 | Roxithromycin Capsule | 5 days | 1. TER | 1. T>C(p<0.01) C : 88.88% T : 95.55% | NR |
| T : 45 | Eungyo-san |
| Wang14) (2013) | C : 62 | Cephalexin Capsule | 7 days | 1. TER | 1. T>C(p<0.05) C : 82.26% T : 96.77% | C : 11.29%T : 3.23% |
| T : 62 | Gyoha-tang |
| Zhong15) (2016) | C : 60 | Cefuroxime Axetil | 5 days | 1. TER2. Symptom Score ① Sore Throat ② Throat Burning Sensation ③ Pharyngeal examination3. Peripheral Blood Percentage ① WBC ② Neutrophils | 1. T>C(p>0.05) C : 90.0% T : 91.7%2. T>C(p<0.001) ① C : 3.55±1.06 → 2.30±0.79 T : 3.60±0.95 → 1.16±0.62 ② C : 2.82±1.26 → 1.59±0.72 T : 2.65±1.33 → 0.35±0.77 ③ C : 3.93±1.07 → 2.35±0.75 T : 3.80±1.21 → 1.10±0.783. ① T>C(p>0.05) C : 8.01±2.45 → 6.31±1.65 T ; 8.13±2.37 → 6.23±1.78 ② T>C(p<0.05)C : 73.21±3.12 → 62.12±2.45T : 72.30±3.05 → 61.35±2.13 | C : 0%T : 0% |
| T : 60 | Sigeumyiin-tang |
| Guo16) (2017) | C : 30 | Amoxicillin | 7 days | 1. TER2. Symptom Score | 1. T>C(p<0.05) C : 83.33% T ; 93.94%2. T>C(p<0.01) C : 19.80±4.05 → 4.62±1.34 T : 20.73±3.86 → 2.81±1.59 | NR |
| T : 33 | Cheonginchisi-tang |
| Li17) (2017) | C : 30 | Amoxicillin | 5 days | 1. TER2. Symptom Score ① Sore Throat ② Pharyngeal Dryness and Burning Sensation ③ Pharyngeal Mucosal Congestion ④ Cough ⑤ Sputum ⑥ Overall | 1. T>C(p<0.05) C : 73.3% T : 90.3%2. T>C(p<0.05)① C :2.70±0.47 → 1.40±0.68 T : 2.93±0.25 → 0.77±0.82② C : 2.57±0.50 → 1.23±0.63 T : 2.70±0.47 → 0.77±0.82③ C : 2.57±0.57 → 1.47±0.63 T : 2.73±0.57 → 1.17±0.15④ C : 2.10±0.55 → 0.83±0.59 T : 2.47±0.57 → 0.27±0.45⑤ C : 2.23±0.63 → 1.0 0±0.79 T : 2.43±0.63 → 0.50±0.78⑥ C :12.10±0.92 → 6.00±2.21 T : 13.27±1. 31 → 3.43±2.42 | C : 26.7%T : 6.7% |
| T : 30 | Cheonginhadam-tang |
| Zhou18) (2019) | C : 40 | Compound BoraxGargle & Amoxicillin | 7 days | 1. TER2. Symptom Score3. Peripheral Blood Percentage ① WBC ② Neutrophils4. Ratio of Peripheral Blood ① IL-2 ② IL-12 ③ IFN-a | 1. T>C(p<0.05) C : 87.50% T : 95.00%2. T>C(p<0.05) C : 21.87±4.38 → 5.68±3.65 T : 20.62±4.61 → 3.26±2.243. T>C(p<0.05)① C : 10.73±1.61 → 6.21±1.79 T : 10.56±1.50 → 6.27±1.76② C : 80.08±4.68 → 58.39±9.25 T : 79.98±4.66 → 57.52±9.024. T>C(p<0.05)① C : 65.58±20.32 → 70.36±20.08 T : 65.56± 20.31 → 73.98±20.06② C : 7.20±1.85 → 7.99±3.02 T : 7.18± 1.84 → 9.05±3.04③ C : 30.17±9.66 → 35.63±10.69 T : 30.15±9.67 → 39.15±10.47 | C : 0%T : 0% |
| T : 40 | Daecheongin-tang |