| Zhong15) (2019) | Remarkably effective- All accumulated blood and exudates are absorbed. | Effective- The accumulated blood and exudate are partially absorbed. | Ineffective- Hemorrhage and exudate are not absorbed or increase. |
| Ai16) (2018) | Remarkably effective- 2 or more improvements in the amount of retinal hemorrhage, exudation, or the number of retinal. microaneurysms- Blood vessel diameter dilatation of more than 10%.- Improved vision by 3 lines or more. | Effective- 1 Improvement in the amount of retinal hemorrhage, exudation, or the number of retinal microaneurysms.- Blood vessel diameter dilatation of more than 5%- Improved vision by 1 lines or more. | Ineffective- No change in all aspects, or even worsening and vision loss. |
| Tang17) (2013) | Remarkably effective- Two-thirds of vision, fluorescein angiography, and retinal changes have improved but have not fully reached normal indicators. | Effective- Patients' symptoms and indicators improved after treatment, but not clear. | Ineffective- Patients' symptoms and indicators do not improve and continue to deteriorate after treatment. |
| Tang18) (2011) | Remarkably effective- Improved vision by 4 lines or more.- In fundus changes, two or more indicators among microaneurysm, hemorrhage, and exudate changes meet the requirements.- In fundus fluorescein angiography, the mean retinal circulation time is significantly shortened, macular edema is significantly reduced, the degree of retinal capillary non-perfusion is significantly reduced, and vascular leakage is significantly reduced. Two or more change indicators meet the requirements and the degree of change is ≥ 20%. | Effective- Improved vision by 2 lines or more.- In fundus changes, one indicator among microaneurysm, hemorrhage, and exudate changes meet the requirements.- In fundus fluorescein angiography, one or more change indicators meet the requirements and the degree of change is ≥ 10%. | Ineffective- Each indicator does not meet the valid criteria.Deterioration- Visual acuity deteriorates by more than 2 lines, proliferative changes in new blood vessels are found, or enlarged retinal capillary non-perfusion areas, worsening macular edema, and increased vascular leakage are observed on fundus fluorescein angiography. |
| Lu20) (2020) | Not Reported | | |
| Yang21) (2019) | Remarkably effective- The eye symptoms were significantly reduced or disappeared, the visual acuity improved by ≥ 4 lines, and the amount of retinal hemorrhage the number of retinal microaneurysms, and fundus exudation were improved by ≥ 2 items. | Effective- The eye symptoms were significantly reduced, with 2 lines ≤ visual acuity improvement < 4 lines, and symptoms such as the amount of retinal hemorrhage, the number of retinal microaneurysms, and fundus exudation were improved. | Ineffective- The eye symptoms did not improve significantly, the visual acuity improved < 2 lines or even regressed, and there was no improvement in the amount of retinal hemorrhage, number of retinal microaneurysms, fundus exudation. |
| Qu22) (2009) | Remarkably effective- Retinal bleeding spots, hard exudates, and cotton wool spots were significantly reduced, no increase in microaneurysms changes, and visual acuity improved by more than 4 lines. | Effective- Retinal bleeding spots, hard exudates, and cotton wool spots were significantly reduced, no increase in microaneurysms changes changes, and visual acuity improved by more than 2 lines. | Ineffective- No change or increase in retinal bleeding spots, hard exudates, and cotton wool spots, an increase in microaneurysms changes, and no improvement or decrease in visual acuity. |