| Phase | Screening | Treatment | |
|---|---|---|---|
| Visit | Screening visit | Visit 1(Baseline) | Visit 2(Final) |
| Time | 2 weeks before-Week 0 | Week 0 | 2 weeks after |
| Written consent | ● | ||
| Sociodemographic information | ● | ||
| Medical history | ● | ||
| Medication history | ● | ● | ● |
| Eligibility criteria | ● | ||
| Random allocation | ● | ||
| Anthropometry | ● | ||
| Vital signs | ● | ● | ● |
| The Hanifin and Rajka criteria | ● | ● | |
| Photographing test lesions | ● | ● | |
| L-SCORAD index | ● | ● | |
| IGA scale | ● | ● | |
| SCORAD index | ● | ● | |
| DLQI | ● | ● | |
| Pruritus VAS | ● | ● | |
| Dryness VAS | ● | ● | |
| Skin hydration | ● | ● | |
| TEWL | ● | ● | |
| Visit guide | ● | ● | |
| Provide experimental products | ● | ||
| Withdraw offered products | ● | ||
| Compliance assessment | ● | ||
| Adverse events | ● | ||
| Satisfaction survey | ● | ||