Table 3. Coregenes of PPI Network of Intersection Targets between Compounds(Ponciri Fructus) and Disease(Dermatitis or Eczema with Pruritus)

Protein name Betweenness Closeness Degree Eigenvector
SRC 326.5875 0.155462 17 0.400926
AKT1 172.7779 0.152893 15 0.38189
EGFR 102.166 0.149194 11 0.300265
PIK3CA 88.62698 0.14741 11 0.295912
STAT1 73.17609 0.149194 10 0.280089
ESR1 74.88208 0.14741 8 0.230545
AR 64.66621 0.146825 7 0.196903
MMP9 147.0203 0.145669 8 0.169802
NOS2 72.40722 0.143411 6 0.157882
AHR 158.3911 0.143969 7 0.144069
PPARG 67.88817 0.142857 5 0.145992
PTGS2 76.28571 0.141762 6 0.139572