| Pan(2013) | 80(40:40) | T : 22/18(26.60±5.25)C: 24/16(25.68±3.95) | T : 22-37C : 19-35 | 黄连阿胶汤2 times/day12wks | γ-Oryzanol+ Vit B112wks | 1. Effective rate N(%)*总有效=显效+有效 | T : 25(62.5%)C : 33(82.5%) | NR |
| Lai(2015) | 102(53:49) | T : 28/25(54.5±3.25)C: 27/22(56.1±3.41) | NR | ① 气血亏虚型 : 当归补血汤合四君子汤② 阴虚火旺型 : 当归六黄汤③ 气虚血瘀型 : 血府逐瘀汤2 times/day.(If there is no improvement after taking 4d, take another 4d) | γ-Oryzanol 20㎎m+ Vit B6 20㎎3 times/day(If there is no improvement after taking 4d, take another 4d) | 1. Effective rate N(%)*总有效=显效+有效 | T : 48(90.6%)C : 29(59.2%) | NR |
| Huang(2015) | 70(35:35) | 38/32(51.8±3.4) | 43-78 | 当归六黄汤2 times/day2wk | γ-Oryzanol 20㎎3 times/day+Western medicine hypoglycemic or insulin therapy(Detail information was not reported) | 1. Effective rate N(%)*总有效=显效+有效1) 显效 : Symptoms have improved significantly. Night and day sweating decreased2) 有效 : Night sweating decreased. Day sweating has no improvement.3) 无效 : Symptoms have no improvement or being worse. | T : 31(88.57%)C : 18(51.43%) | NR |
| Li(2016) | 60(30:30) | T : 17/13(3.42±1.51)C: 16/14(3.56±1.45) | T : 1-11mC : 1-12m | 三甲复脉汤3wk | γ-Oryzanol 10-30㎎3 times/day | 1. Effective rate N(%)*总有效=痊愈+显效+有效1) 痊愈 : Symptoms disappeared. Score = 02) 显效 : Symptoms have improved significantly. Score decreased ≥66.67%3) 有效 : Symptoms have improved. Score decreased ≥33.33% and <66.67%4) 无效 : No improvement in clinical symptoms. Score decreased <33.33%2. TSS | T : 28(93.33%)C : 25(83.33%) | NR |
| Yuan(2016) | 58(29:29) | T : 0/29(50.03±4.0.31)C: 0/29(50.52±3.738) | T : 45-55C : 45-55 | 更年止汗汤2 times/day3wk | γ-Oryzanol10-20㎎+Vit C 100-200㎎3 times/day3wkCalcium Carbonate D3 600㎎2 times/day3wk | 1. Effective rate N(%)*总有效=治愈+好转1) 治愈 : Sweating and other clinical symptoms disappeared.2) 好转 : Sweating has improved significantly. Other clinical symptoms has improved.3) 无效 : Sweating and other clinical symptoms has no improvement or been worse. | T : 26(89.65%)C : 20(68.96%)Significant differences between T : and C : (p<0.05) | NR |
| Wang(2019) | 45(22:23) | T : 11/10(35.6±8.8)C: 12/11(35.2±8.6) | T : 24-64C : 26-62 | 桂枝汤3 times/day14d | Atropine Sulfate Injection 1㎎2 times/day14d | 1. Effective rate N(%)*总有效= 治愈+效果显+有效果1) 治愈 : Sweating disappeared in 5d and didn't recur in 2d.2) 效果显 : Sweating disappeared in 6-10d and didn't recur in 2d.3) 有效果 : Sweating disappeared/improved in 11-15d and didn't recur in 2d.4) 无效 : Sweating has no improvement | T : 19(86.4%)C : 15(63.6%) | Side effect N(%)T : 口乾 5(22.7%) 潮熱 3(13.6%) 煩燥 2(9.1%)C : 口乾 9(39.1%) 潮熱 6(26.1%) 煩燥 5(21.7%) |
| Kong(2020) | 120(60:60) | T : 32/28(2.65±1.17m)C: 33/27(2.64±0.84m) | T : 1-6mC : 1-5m | 三甲复脉汤3 times/day8wk | γ-Oryzanol 10-30㎎3 times/day. | 1. Effective rate N(%)总有效率 = (治愈 + 显效 + 有效)/ 总例数 ×100%1) 治愈 : Sympmtom has disappeared. TCM score = 02) 显效 : Symptoms has improved significantly TCM score decreased >70%3) Symptoms has improved. TCM score decreased <70% and >30%4) 无效 : No improvement. TCM score <30%.2. TSS | T : 57(95.00%)C : 48(80.00%) | NR |
| Zhou(2021) | 92(46:46) | NR | NR | 当归六黄汤2 times/day4wk | Vit B12 0.5㎎,+Vit B1 10㎎3 times/day+Western medicine hypoglycemic or insulin therapy.(Detail information was not reported) | 1. Effective rate N(%)总有效率 =( 治愈 + 好转)/ 总例数 ×100%1) 治愈 : Sympmtom has disappeared. BST is being stable in normal range2) 好转 : Symptoms has improved significantly BST is in normal range3) 无效 : No improvement. BST is being changeable or higher2. Blood test index : FPG, 2hPG, HbA1c, TG, LDL-C, Blood viscosity, FIB | T : : 43(93.48%)C : : 34(73.91%) | Incidence of adverse reactions such as dizziness, fatigue, nausea and vomiting in the two groups has no significant difference(p>0.05). |