Table 1. Summary of Included Studies

First Author (Year) Sample Size Intervention Comparison Period Outcome Measurement Results Adverse events
Chin7) (2009) 玫瑰糠疹(n=96) 丹茜化斑湯(n=48)1Pk bid Loratadine 10㎎ 1T QdVitamin C 0.2g 1T tidCalamine lotion(n=48) 3 Wks Cure : The rash subsides and the itching disappears.Improve : The rash subsided by more than 30%, sometimes mild itchingInvalid : Less than 30% of the rash subsided [Cure rate /Efficient rate]I : 85.4% /97.9%O : 64.5% /85.4% Intervention : 2 casesComparison : 4 cases
Xie8) (2002) 玫瑰糠疹(n=70) 凉血消疹湯(n=40)1Pk Qd Chlorpheniramine 4㎎ 1T tidVitamin C 0.2 g 1T tid(n=30) 20 Ds Cure : Skin lesions completely resolvedImprove : Skin lesions resolved more than 30%Invalid : Less than 30% of skin lesions resolved [Efficient rate]I : 92.5%O : 60% N-S
Hao9) (2014) 玫瑰糠疹(n=80) Traditional Chinese Herbal Medicine(n=40) Cetirizine HCl 10㎎ 1T QdVitamin C 0.1g 1T tid(n=40) 4 Wks Cure : The rash subsides and the itching disappearsEffective : 60% of the rash subsided, sometimes mild itchingImprove : The rash subsided by 30%, with mild itchingInvalid : The rash does not disappear significantly, and the pruritus improves slightly or does not change [Effective rate /Efficient rate]I : 65.0% /87.5%O : 32.5% /67.5% N-S
Xiao10) (2015) 玫瑰糠疹(n=88) 銀翹消斑湯(n=45)1Pk bid NB-UVB 2 Wks Cure : Skin lesions resolved ≥95%, no new rashEffective : 94%-70% of the skin lesions subsided, and the inflammatory reaction was significantly relievedImprove : The skin lesions disappeared 69%-30%, and there is still a small amount of new rash after the treatment is overInvalid : The skin lesions resolved less than 30%. After the treatment, most new skin rashes still appeared, and the inflammatory reaction was not controlled. [Efficient rate]I : 88.90%O : 65.12%(Efficient rate : Cure rate + Effective rate) N-S
Wang11) (2012) 玫瑰糠疹(n=78) 銀翹散合化斑湯(n=40)1Pk bid Cetirizine HCl 10㎎ 1T QdVitamin C 0.2g 1T tid(n=38) 3 Wks Cure : All skin lesions disappeared, leaving only pigmentation or diminished spotsEffective : Skin lesions resolved ≥75%, erythema fadedImprove : Skin lesions resolved ≥30%Invalid:Skin lesions resolved <30% [Effective rate /Efficient rate]I : 90.00% /95.00%O : 55.26% /68.42% N-S
Xu12) (2006) 玫瑰糠疹(n=72) 銀翹散加味(n=38)1Pk Qd Cetirizine HCl 10㎎ 1T QdRivavirin 300㎎ 1T tid(n=34) 4 Wks Cure : All skin lesions subsided, only temporary pigmentation spots and scaling are left, and the itching disappearsEffective : More than 70% of the skin lesions have subsided, and the itching has been significantly reduced or basically disappearedImprove : Skin lesions subsided by more than 50%, pruritus reducedInvalid : Less than 50% of the skin lesions resolved or no changeEfficient rate : Cure rate + Effective rate [Efficient rate]I : 86.8%O : 64.7%(Efficient rate : Cure rate + Effective rate) Intervention< Comparison
Lyu13) (2011) 玫瑰糠疹(n=100) 消銀膠囊(n=50)1C tid Cetirizine HCl 10㎎ 1T Qd(n=50) 2 Wks Cure : The skin lesions have completely subsided and the inflammation has disappearedEffective : For skin lesions resolved ≥70%, inflammation was significantly reducedImprove : 30%-69% of skin lesions subsided, inflammation reducedInvalid : For skin lesions subsided <30% [Efficient rate]I : 98%O : 82%
Sun14) (2018) 顽固性 玫瑰糠疹(n=110) 凉血透疹渗濕湯(n=55)1Pk bid Glycyrrhizin+5% glucose inj.Mometasone oint.(n=55) 2 Wks Cure : The skin lesions disappeared completely, no recurrence within half a year after stopping the drugEffective : The skin lesions are reduced by 70% and above, and there is basically no recurrence after stopping the drug for half a yearImprove : The skin lesions are reduced by 30%-69% or less, and there is a recurrence after stopping the drug for half a yearInvalid : Reduction of skin lesions <30%Total Efficient rate = (Cure + Effective + Improve)/Total sample size×100% [Pruritus reduction time]I : 6.8±2.2O : 10.6±1.7[Efficient rate]I : 98.18%O : 80.00%[Recurrence rate]I : 0%O : 6% Intervention : 1 caseComparison : 8 cases
Gao15) (2011) 玫瑰糠疹(n=140) 凉血透疹渗濕湯(n=72)1Pk bid Glycyrrhizin+5% glucose inj.(n=68) 2 Wks Cure : Skin lesions completely resolvedImprove : Skin lesions resolved ≥30%Invalid : Skin lesions resolved <30% [Efficient rate]I : 100%O : 85.3% Intervention : 0 caseComparison : 3 cases