Table 3 Effect of PKS Oil to Expression of Proteins

Investigated protein		Looking forward efficiency	Efficiency (% of control)
Investigated protein		Looking forward efficiency	PKS oil
Collagen synthesis pathway	P4H2	Up regulation	123.8
	P4H3		159.2
	P3H2		101.7
	P3H3		368.1
	LH1		224.8
	LOX		160.3
MMPs	MMP-1	Down regulation	74.6
MMPs	MMP-12	Down regulation	94.2
ECM-cell interaction	Integrin B5	Up regulation	109.7
ECM-cell interaction	Integrin B7	Up regulation	149.0
Cytokines	TGF-b3	Down regulation	82.1
	IL-1b		79.7
	IL-6		76.4
Antioxidant enzymes	catalase	Up regulation	321.1
Antioxidant enzymes	GRM	Up regulation	103.8

The expression of protein from the human dermal fibroblast cells, which was treated with PKS, was compared with control.