Table 2. The schedule of clinical trial

Period	-	Treatment phase		Follow-up phase
Visit	Screening	1	2	3
Week	-10 D	0	1	2
Consent	✔
Demographic investigation	✔
Medical history	✔
Vitals sign	✔	✔	✔	✔
Body measurement	✔
Clinical laboratory test	✔		✔
Criteria of selection and exception	✔
Korean medical demonstrative classification		✔
Randomization		✔
Providing cream		✔
PSS	✔	✔	✔	✔
Skindex-29		✔	✔	✔
Corneometer		✔	✔	✔
Tewameter		✔	✔	✔
Testing abnormal response		✔	✔	✔
Clarification of medicine		✔	✔	✔
Site Visit education		✔	✔