Table 2. Characteristics of articles of Acupuncture for AD

Author Sample size Style of aupuncture Acupoint(I) Treatment session & period (I) Time(I) Intervention Group Control group Outcome measurements Main result(I/C) Safety
Florian Pfab (2011)8) 10 (5/5) 0.25×40㎜ Quchi(LI 11),Hegu(LI 4),ZuSanLi(ST 36),Xuehai(SP 10). 2 per a week/total 5 weeks(total 10) 20 min. Acupuncture NO 1.SCORAD Index2.VAS(Visual Analog Scale)3.BAT(Basophil Activation Test) 1. I=C(day 15 - day 0)I:-6.1 ± 10.1C:4.4 ± 1.6(day 33 - day 0)I:-5.6 ± 17.6C:3.5 ± 3.42. I<C(day 15 - day 0)(p = 0.024)I:-25% ± 26%C:15% ± 6%(day 33 - day 0)(p = 0.022)I:- 24% ± 31%C:29% ± 9%3. I > C(day 15 - day 0)(p = 0.024) N.R
Florian Pfab (2012)9) 20 0.25×40㎜ LI11,HT3,ST34,SP10 2 per a week/total 5 weeks(total 10) 20 min. AcupunctureVA(VAp. VAa) S.A (PAp, PAa) NI 1.VAS,2.EIQ(Eppendorf Itch Questionnaire) 1. VASㆍFlare sizeNI>VAp>PapNI>PAa>VAaㆍWheal sizeNI>Pap>VApNI>PAa>VAa2. EIQㆍEIQ descriptiveNI>VAp>PapNI>PAa>VAaㆍEIQ emotionalNI>Pap>VApNI>PAa>VAa -
Kang SH (2018)10) 30 (VA1=10, VA2=10, SA=10) 0.25×40㎜ 6 basic pointsLI11,ST36,PC6 VA1:3 per a week/total 4 weeks (total 12)VA2:2 per a week/total 4 weeks (total 8)SA:2 per a week/total 4 weeks (total 8) 15 min AcupunctureVA1VA2 S.A 1.SCORAD index2.VAS3.EASI4.POEM5.DLQI6.CES-D 7.STAXI 1. VA1=VA2<S.A)2. VA1=VA2<S.A)3.VA1=VA2=S.A4.VA1=VA2=S.A5.VA1=VA2<S.A6.VA1=VA2=S.A7.VA1=VA2=S.A contusion (n = 3).N.R
Lee HC (2019)11) 14(7 / 7) 0.25×40㎜(Acu)31G×25 ㎜, (Needle-embedding) Quchi(LI11) A group3 per a week/total 4 weeks (total 12)NA group1 per a week/total 4 weeks (total 4) 20 min. Acupuncture needle-embedding 1.SCORAD index2.TEWL3.Skin hydration4.DLQI 1. I=C2. I=C3. I=C4. I=C N.R
N.A : no acupuncture intervention, VAS : Itch intensity (VAS) CT : Common acupuncture
I : Intervention Group, C : Control group, S.A : Sham acupuncture