Table 4. Subjects and Methods in the Review Studies

No. 1st Auther (year) Subject Method 1 Method 2
1 Ji Geun-Eok (2005) Probiotics in Prevention Allergy 22) PR* Presentation of the literary reviews on allergic and atopic developmental mechanisms and allergic reduction effect of probiotics and the animal test results
Result
In the Ovalbumin-induced allergic mouse model, allergy was reduced when probiotics were orally administered. The timing of Bifidobacterium affects the incidence of OVA allergy in mice, and it was most effective when it was administered before the occurrence of allergy. All the living cells, heat-treated dead cells and crushed cells of Bifidobacteria were effective, but living bacteria were most effective.
2 Jeong Seok-Geun et al. (2007) Anti-Allergy Effect of Lactic Acid Bacteria23) PR* Survey of anti-Allergy Effect of Lactic Acid Bacteria
Result
The immune boosting effect of lactic acid bacteria has been scientifically recognized, and the immune boosting can be converted to allergic prevention effects. It has been reported that the probiotics such as lactic acid bacteria can act as a defense against early onset of allergies and thus for early atopy, but more verification is required.
3 Ji Geun-Eok et al. (2007) Understanding Allergies and Preventing Allergies with Probiotics Lactobacillus24) Bifidus BGN4, Bifidus AD011, Lactobacillus AD031 Study of Probiotics Effects on Atopic Dermatitis through Animal and Clinical Experiments
Result
1. Oral administration of lactic acid bacteria, such as BGN4, to mice with peanut-induced allergy reduced allergic symptoms.2. The results of experimental papers showing low incidence of atopic dermatitis after ingestion of lactic acid bacteria such as BGN4 before and after delivery to pregnant women with atopic family history were analyzed to check if probiotics were effective for atopic dermatitis.
4 Seo Jae-Gu et al. (2010) Development of Probiotic Products and Challenges25) PR* Probiotics development trend, probiotic product stability and functionality research
Result
To date, the probiotic market is dominated by living bacteria-oriented products, but products made of dead bacteria and antimicrobial agents such as bacteriocins should also be studied, and the clinical studies on improvement effects for immune diseases such as atopy should be continued.
5 Baek Yeong-Mi et al. (2010) Health Improvement and Treatment Effect of Probiotics 26) Data were collected by searching related papers on Pubmed and RISS Domestic and foreign papers and clinical reports demonstrating the efficacy of probiotics treatment, and reviews on applicable diseases
Result
Probiotics are effective in the treatment of atopic dermatitis. And it is better to consume the probiotics in harmony with the interaction between probiotics and the human host.
6 SeppoSalminen et al. (2011) LGG: Effects on Intestinal Immunity, Allergies and Obesity 27) PR* Efficacy Study of Lactobacillus GG
Result
Lactobacillus rhamnosus GG has its own peculiarities and is effective in allergic disease, obesity and intestinal immunity.
7 Hwang Ji-Seon et al. (2012) Probiotics as an Immune Modulator for Allergic Disorders28) PR* Efficacy, Mechanism of Probiotics, Current Status and Research for Atopic Dermatitis and Allergy Treatment
Result
In the prevention and treatment of atopic dermatitis and allergic diseases using probiotics, the results may vary depending on the type of probiotics, the dosage and the duration of ingestion.
8 Lim Gwang-Se et al. (2014) Bioactive Molecules Produced by Probiotics to Control Enteric Pathogens29) PR* Health functional research of probiotics
Result
The health functions of probiotics include the followings: reducing the incidence of colorectal cancer and other colon-related diseases such as Colorectal Cancer and IBS; relieving the atopic dermatitis by promoting the immune system; antihypertensive and anticholesterol effects; reducing the effects of antibiotics on intestinal bacteria; preventing the gastrointestinal tract infections.
9 An Kang-Mo (2015) The preventive and Therapeutic Effect of Probiotics in Allergic Diseases30) PR* Study on preventive and therapeutic effect of orally administered probiotics in allergic diseases
Result
When probiotics were given to pregnant women with atopic family history before delivery, the incidence of atopic dermatitis was lower in newborns after birth. And when probiotics were administered to patients with atopic dermatitis, the severity was reduced.
PR; personal research of data.