1 | Lee Ki-Sun et al. (2007) | Selection of Anti-Allergic Lactobacillus in Murine Model of Peanut Allergy14) | 5-week-old C3H/HeJ mice were sensitized by administration of peanut protein to the gastrointestinal tract, and then treated with Lactobacillus monoclonal culture strains. to select strains with the most effect | 5-week-old C3H/HeJ |
Result |
Lactobacillus species that reduced peanut-specific IgE were checked and found that L. casei IBS041, L. casei 346, L. casei 699, and L. acidophilus AD031 decreased the production of IgE antibodies by 50% or more than reference group. |
2 | Lee In-Hoe et al. (2008) | Effects of probiotic extracts of Kimchi on immune function in NC/Nga mice15) | L.plantarum K8 lysate and Lactobacillus mixture (L.rhamnosus GG, B. lactis Bb-12Lb, L. plantarum K8, L. plantarum K8 lysate, γ-linolenic acid) were orally administered for 4 weeks | 6-week-old NC/Nga mice |
Result |
Oral administration of lactobacillus lysate and a mixture of lactic acid bacteria and gamma-linolenic acid reduced the serum IgE, IL-4, and IL-5, and was effective in treating atopy. |
3 | Kim Seong- Beom et al. (2011) | Antiinflammatory and Antiallergic Activity of Fermented Turmeric by Lactobacillus johnsonii IDCC 920316) | Turmeric fermented by L. Johnsonii IDCC 9203 was orally administered for 5 weeks | 5-week-old NC/Nga mice |
Result |
Turmeric material fermented by L. Johnsonii IDCC 9203 increases the curcuminoid, an active ingredient, strengthening the anti-inflammatory and anti-allergic activity of turmeric. |
4 | Choi Mi-Ok et al. (2013) | Anti-allergic activities of Castanea crenata inner shell extracts fermented by Lactobacillus bifermentans17) | Castanea crenata inner shell extracts fermented by Lactobacillus bifermentans were applied for 3 weeks | 6-week-old NC/Nga mice |
Result |
Groups treated with fermented Castanea crenata extracts showed the decreased skin erythema and inhibited the expression of inflammatory cytokines IL-1β and TNF-α, proving the effects in treating atopy. |
5 | Kim Bae-Jin et al. (2013) | Anti-atopic effects of castanea crenata inner shell extracts fermented by Lactobacillus bifermentans18) | Castanea crenata inner shell extracts fermented by L.bifermentans were applied to DNCB-coated Na/Nga mice in different concentrations(0.1%, 1%, 5%) | 6-week-old Nc/Nga mice |
Result |
No change in body weight was observed between the two groups, but the scores indicating the severity of symptoms decreased in the group treated with Lactobacillus-fermented castanea crenata. Skin melanin index, erythema index, water index and spleen levels, IL-1β, TNF-α, and serum IgE contents were all decreased in the group applied by Lactobacillus-fermented castanea crenata. |
6 | Lee Seung- Hun et al. (2016) | Anti-allergic effect of Lactobacillus rhamnosus IDCC 3201 isolated from breast milk-fed Korean infant19) | Oral administration of L. rhamnosus GG ID3201 as dead cell bodies and supernatant concentrate | BALB mouse |
Result |
In the group that L. rhamnosus IDCC3201 cell bodies isolated from breastfeeding feces and their cultures were orally administered, there was an atopic therapeutic effect through immunobalance. |