Table 2. Methods of Treatment and Evaluation in the Animal Experiment

No. 1st Auther (year) Subject Method Species of Animals
1 Lee Ki-Sun et al. (2007) Selection of Anti-Allergic Lactobacillus in Murine Model of Peanut Allergy14) 5-week-old C3H/HeJ mice were sensitized by administration of peanut protein to the gastrointestinal tract, and then treated with Lactobacillus monoclonal culture strains. to select strains with the most effect 5-week-old C3H/HeJ
Result
Lactobacillus species that reduced peanut-specific IgE were checked and found that L. casei IBS041, L. casei 346, L. casei 699, and L. acidophilus AD031 decreased the production of IgE antibodies by 50% or more than reference group.
2 Lee In-Hoe et al. (2008) Effects of probiotic extracts of Kimchi on immune function in NC/Nga mice15) L.plantarum K8 lysate and Lactobacillus mixture (L.rhamnosus GG, B. lactis Bb-12Lb, L. plantarum K8, L. plantarum K8 lysate, γ-linolenic acid) were orally administered for 4 weeks 6-week-old NC/Nga mice
Result
Oral administration of lactobacillus lysate and a mixture of lactic acid bacteria and gamma-linolenic acid reduced the serum IgE, IL-4, and IL-5, and was effective in treating atopy.
3 Kim Seong- Beom et al. (2011) Antiinflammatory and Antiallergic Activity of Fermented Turmeric by Lactobacillus johnsonii IDCC 920316) Turmeric fermented by L. Johnsonii IDCC 9203 was orally administered for 5 weeks 5-week-old NC/Nga mice
Result
Turmeric material fermented by L. Johnsonii IDCC 9203 increases the curcuminoid, an active ingredient, strengthening the anti-inflammatory and anti-allergic activity of turmeric.
4 Choi Mi-Ok et al. (2013) Anti-allergic activities of Castanea crenata inner shell extracts fermented by Lactobacillus bifermentans17) Castanea crenata inner shell extracts fermented by Lactobacillus bifermentans were applied for 3 weeks 6-week-old NC/Nga mice
Result
Groups treated with fermented Castanea crenata extracts showed the decreased skin erythema and inhibited the expression of inflammatory cytokines IL-1β and TNF-α, proving the effects in treating atopy.
5 Kim Bae-Jin et al. (2013) Anti-atopic effects of castanea crenata inner shell extracts fermented by Lactobacillus bifermentans18) Castanea crenata inner shell extracts fermented by L.bifermentans were applied to DNCB-coated Na/Nga mice in different concentrations(0.1%, 1%, 5%) 6-week-old Nc/Nga mice
Result
No change in body weight was observed between the two groups, but the scores indicating the severity of symptoms decreased in the group treated with Lactobacillus-fermented castanea crenata. Skin melanin index, erythema index, water index and spleen levels, IL-1β, TNF-α, and serum IgE contents were all decreased in the group applied by Lactobacillus-fermented castanea crenata.
6 Lee Seung- Hun et al. (2016) Anti-allergic effect of Lactobacillus rhamnosus IDCC 3201 isolated from breast milk-fed Korean infant19) Oral administration of L. rhamnosus GG ID3201 as dead cell bodies and supernatant concentrate BALB mouse
Result
In the group that L. rhamnosus IDCC3201 cell bodies isolated from breastfeeding feces and their cultures were orally administered, there was an atopic therapeutic effect through immunobalance.