| Valid. 23 papers (76.7%) | 1. Reduction of inflammatory cytokine19,31,41,42,49,50,52) | 7 papers(30.4%) |
| 2. Reduction of SCORAD score31,41,42,50,52) | 5 papers(21.7%) |
| 3. Increase of inflammatory inhibitory cytokines16,21,34,35) | 4 papers(17.3%) |
| 4. Reduction of serum IgE14,15,18) | 3 papers(13.0%) |
| 5. Inhibition of Mast Cell Degranulation20,21) | 2 papers(8.7%) |
| 6. Improvement of stratum corneum36) | 1 paper (4.3%) |
| 7. Increase of cell survival rate46) | 1 paper (4.3%) |
| Not valid. 9 papers (30%) | 1. No difference between control group and experimental group31,43-45,48,54). | 6 papers(66.7%) |
| 2. Effective for eczema but not for atopy46). | 1 paper(11.1%) |
| 3. Not effective within 1 year after ingestion53). | 1 paper(11.1%) |
| 4. Depends on the period, but little effective51). | 1 paper(11.1%) |