Table 18. Change of Skin Hydration between Treatment Group and Control Group in Baseline and 6 weeks(Center between the medial aspect of the elbow and the wrist)

	Descriptives	V2	V4	Difference	p–value
Control Group	n	24	24	24	0.000b
	Mean±SD	25.911±6.136	31.696±5.528	5.785±6.431
	Median	26.250	30.700	5.233
	Min	17.133	19.900	−1.467
	Max	36.100	40.800	21.167
Treatment Group	n	23	23	23	0.000a
	Mean±SD	28.307±6.470	39.380±6.593	11.072±8.998
	Median	28.633	38.367	9.233
	Min	15.600	30.233	−0.034
	Max	38.967	58.033	32.167
p–value		0.199c	0.000c	0.024d

p-value by paired t-test
p-value by Wilcoxon signed rank test
p-value by Independent two-sample t-test
p-value by Mann-Whitney test