| Guo F (2010)49) | China | Bell’s palsy | 40 (20/20) | >2m | Atx, HM | Atx | 1c: 6t/w,Total 3c | ① Endothelial pigment level② H-B③ Effective rate | ① 0.49±0.01 (p<0.05)② improved (p<0.05)③ 90% (p<0.05) | ① 0.27±0.00② improved (p<0.05)③ 60% (p<0.05) | Effective, Safe |
| Hong Y (2011)50) | China | Bell’s palsy | 82 (52/30) | >3m | Atx, HM | Atx | Atx: 2t/w,HM: bid,Total 6m | H-B (effective rate) | 98.07% (p<0.01) | 86.67% | Effective,Safe |
| Huang Z (2011)51) | China | Bell’s palsy | 78 (40/38) | Mean 4.2m | Atx(gold),Moxa | Atx(steel), Moxa | Qd,1c: 10t,Total 2c | H-B (effective rate) | 95.0% (p<0.05) | 86.8% | Effective |
| Jia H (2012)53) | China | Bell’s palsy | 316 (158/158) | >6m | Atx,Moxa,Puncture bleeding,Acupoint injection,HM | Atx | Qd,(inj: qod, HM: bid)1c: 10d,Total 4c | Self-evaluation tool① Markedly effective② Effective③ Ineffective | ① 69 cases② 74 cases③ 15 cases | ① 27 cases② 75 cases③ 56 cases | Effective |
| Between T, C: p<0.05Between ①(T, C): p<0.01 |
| Liu L (2012)54) | China | Bell’s palsy | 60 (30/30) | >3m | Atx(wrist),Infrared,Face exercise | Atx,Infrared | 1c: 10d,Total 3c | Effective rate | 96.67% (p<0.01) | 73.33% | Effective |
| Wang X (2012)52) | China | Bell’s palsy | 60 (30/30) | >6m | Needle-embedding therapy | Atx | 1t/7~15d,1c: 4tTotal c is not stated. | Effective rate | 80.0% | 77.78% | Needle-embedding therapy can replace Atx. |
| Between T, C: p>0.05 |
| Wu G (2013)55) | China | Bell’s palsy | 80 (40/40) | >2m | Atx (penetration) | Atx | Qd,1c: 2w,Total 2c | Effective rate | 92.5% | 72.5% | Effective |
| Between T, C: p<0.05 |
| Ding P (2013)56) | China | Peripheral facial paralysis | 138 (74/64) | >90d | Electro-Atx | Atx | Qod,1c: 10t,Total c is not stated. | Effective rate | 95.9% | 73.4% | Effective |
| Between T, C: p<0.01 |
| Dong YH (2014)59) | China | Peripheral facial paralysis | 80 (40/40) | >3m | Atx,Cut therapy | Atx | Atx: Qod,total 12w.Cut: 1t/3~5d, generally no more than 4t. | Effective rate | 100% | 92.5% | Effective |
| Between T, C: p<0.01 |
| Li W (2014)57) | China | Peripheral facial paralysis | 92 (46/46) | Mean 8.6y | Atx(scalp) | Atx | Qd,1c: 12d,Total 2c | ① Time (a) Facial recovery time (b) Total treatment time② Effective rate③ Relapse rate | ① (d) (a)11.74±1.81 (b)13.85±2.02② 91.3%③ 4.3% | ① (a)8.94±1.36 11.22±1.75② 71.7%③ 28.3% | Effective |
| Between T, C: p<0.05 |
| Li H (2014)58) | China | Peripheral facial paralysis | 60 (30/30) | >3m | Atx (Suihui Xuezu) | Atx | Qd,1c: 6d,Total 3c | H-B (a)Curative rate (b)Total efficacy | (a) 42.3%(b) 100% | (a) 34.8%(b) 91.6% | |
| Guo C (2015)62) | China | Bell’s palsy | 60 (30/30) | 3m~1y | Needle embedding therapy, Moxa | Atx | 2m | H-B (effective rate) | 86.7% | 76.7% | |
| Pourmomeny AA (2015)61) | Iran | Bell’s palsy | 34 (17/17) | >6m | BTX-A,EMG bf | NS,EMG bf | 4m | ① SFGS② Picture③ Video | ① 55.17→74.17 (p<0.01) | ① 66.31→81.37 (p<0.01) | |
| Between T, C: p>0.05 | |
| Kwon HG (2015)60) | South Korea | Bell’s palsy | 39 (26/13) | >6m | Atx | None | 8w | ① FDI (a)Social (b)Physical② H-B③ SFGS④ Lip mobility (a)Length (b)Snout⑤ Stiffness | ① (a) +21.69 (b) +26.16② -0.62③ +24.54④ (a) +1.00 (b) +2.36⑤ -1.58 | ① (a) -1.85 (b)+4.62② -0.38③ +9.77④ (a) -0.25 (b) -0.80⑤ 0 | |
| Li C (2015)64) | China | Peripheral facial paralysis | 80 (40/40) | >2m | Warm needling combined with flash cupping treatment | Atx | 3t/w,Total 4w | ① SFGS② H-B (effective rate) | ①52.825±2.413→81.200±1.438② 90% | ①50.575±3.044→70.475±2.055② 70% | |
| Between T, C: p<0.05 | |
| Sun L (2015)63) | China | Peripheral facial paralysis | 100 (50/50) | >3m | Electro-Atx | IF pulse | 2t/w,Total 20t | ① SFGS (a) Resting (b) Movement② Effective rate | ① (a)2.56±0.48→1.28±0.66 (p<0.05) (b)2.60±0.64→1.79±0.62 (p<0.05)② 58.13% (p<0.05) | ① (a)18.42±2.30→12.30±3.17 (p<0.05) (b)19.22±3.20→14.46±3.85 (p<0.05)② 39.29% | |
| Song Z (2016)66) | China | Bell’s palsy | 60 (30/30) | >3m | Atx (push and pull) | Atx | Qd,1c: 5t,Total 4c | ① H-B② Ten scoring method③ Effective rate | ① p<0.017② 15.86±2.82→9.60±2.19 (p<0.01)③ 96.6% | ① p<0.048② 17.00±3.35→11.86±2.96③ 90.0% | |
| Between T, C③: p<0.033 | |
| Cao J (2016)65) | China | Peripheral facial paralysis | 70 (35/35) | 3m | Atx, HM | Atx | 1c: 6t,Total 3c | H-B(a) Curative rate(b) Efficiency rate | (a) 40.0%(b) 97.7% | (a) 15.6%(b) 78.1% | Effective |
| Between T, C: p<0.05 |
| Li X (2017)68) | China | Ramsay-hunt syndrome | 60 (20/20/20) | >3m | Plum blossom needle, Atx | Plum blossom needle | 1c: 20t(Atx: 10t)Total 2c | ① H-B② SFGS③ Clinical efficacy | ① 4.72±0.30→2.28±0.65 (p<0.05)② 53.56±2.12→97.12±2.58 (p<0.05)③ 95.0% (p<0.05) | ① 4.61±0.36→3.26±0.45 (p<0.05)② 53.87±5.26→74.52±3.23 (p<0.05)③ 70.0% | Effective |
| Atx | ① 4.53±0.44→2.96±0.75 (p<0.05)② 53.56±2.13→82.36±3.43 (p<0.05)③ 85.0% |
| Chen Y (2017)67) | China | Peripheral facial paralysis | 43 (22/21) | Not stated | Electro-Atx, HM, Moxa | Electro-Atx, HM | Qd,1c: 15t,Total 2~12c | Cure rate | 72.73% | 42.86% | Effective |
| p<0.05 |
| Zhang J (2018)70) | China | Bell’s palsy | 70 (35/35) | >3m | Atx,Acupoint injection | Atx | Qd,1c: 12t,Total 2c | ① Ten scoring method② Clinical efficacy | ① 14.60±3.46→6.20±3.46② 82.86% | ① 14.63±3.54→8.60±4.44② 68.57% | Effective |
| P<0.05 |
| Zeng W (2018)69) | China | Peripheral facial paralysis | 87 (43/44) | Not stated | Atx, HM | Atx | Atx: not stated,HM: tid,1c: 6d,Total 3c | Effective rate | 88.64% | 69.77% | Effective |