Table 1. Analysis of the Case Reports

First Author (Year) Country Subject (Sex/Age) Diagnosis Morbidity period Sx Treatments Treatment period (Frequency) Methods of evaluation Results
Wang W (2008)47) China 26 cases(M: 16, F: 10, mean age: 38) Bell’s palsy >6m Hearing impairment,Contracture,Crocodile tears,Facial spasm,Synkinesis HM Qd,1c: 10t,Total 3c Effective rate 96.15%
Choi CH (2009)20) South Korea F/47 Bell’s palsy 2m Contracture,Weakness, Synkinesis Atx, Bee venom PAtx, HM, Infrared, Physiotherapy 55d ① H-B② Y ① Ⅳ→Ⅱ② 19→39
M/38 3m Crocodile tears 47d ① Ⅱ→Ⅱ② 25→40
M/65 3m Contracture, Weakness 21d ① Ⅳ→Ⅲ② 15→26
Chu MG (2009)21) South Korea F/5 Ramsay-hunt syndrome 2m Lagophthalmos,Asymmetry Facial rejuvenation Atx 1m (6) H-B Ⅳ→Ⅱ
F/50 Bell’s palsy 2m Lagophthalmos,Asymmetry 10d (3) Ⅳ→Ⅱ
F/23 6m Lagophthalmos,Asymmetry 1m (6) Ⅳ→Ⅲ
F/40 1m Ptosis, Asymmetry 2m (8) Ⅴ→Ⅱ
F/50 1y Lagophthalmos,Asymmetry 15d (3) Ⅳ→Ⅲ
Won JS (2009)22) South Korea 18 cases(M: 7, F: 11, age: 19~79) Bell’s palsy >2m Eye dryness,Facial pain Paresthesia,Mastoid pain,Facial spasm Atx, Physiotherapy, HM, Aroma therapy 1m ~over 1y H-B Ⅳ→Ⅱ, Ⅰ: 3Ⅲ→Ⅱ, Ⅰ: 7Ⅱ→Ⅰ: 4No change: 4
Komori M (2009)23) Japan F/60 Bell’s palsy 21y Mouth movement disturbance,Synkinesis,Contracture Rehabilitation program (massages, stretching) 4m EMG Little activity of orbicularis oris in any mouth/eye movement
F/61 2y Depressor anguli oris/labii inferioris> orbicularis oris
Shao X (2009)24) China 50 cases(M: 22, F: 28, age: 17~75) Peripheral facial paralysis 3.5~9m Lagophthalmos,Dacryorrhea,Asymmetry Atx 5t/w,1c: 20t,Total c is not stated. Effective rate 90.0%
Álvaro N (2010)25) Spain 48 cases(M: 14, F: 34, mean age: 48) Bell’s palsy Not stated (ENog<10%) Synkinesis,Contracture Physiotherapy, BTX 18m ① SFGS② VAS (satisfaction) ① 56.9%② 7
Fu X (2010)26) China 100 cases(M: 36, F: 64, age: 1~75) Peripheral facial paralysis 3m~1y Facial spasm,Paresthesia Puncture bleeding 2t/w,Until recovery Effective rate 90.0%
Cui Y (2010)27) China M/58 Bell’s palsy 3m Lagophthalmos,Asymmetry Atx Qd,Total 10w Portmann score 8→17
Lee CW (2011)28) South Korea 27 cases(M: 13, F: 14, mean age: 47) Bell’s palsy >3m Not stated Needle-embedding therapy Qw (mean: 2.59) ① Y② Number of Sx (Q)③ Sx score (Q) (mean)① 29.48→33.11② 7.35→6.35③ 5.93→4.71(p<0.05)
Wiener A (2011)29) USA F/50 Bell’s palsy 3m Synkinesis,Facial spasm,Neck pain Neurotoxins, Fillers 6y Picture -
Ai B (2011)30) China M/74 Peripheral facial paralysis 50d Asymmetry,Lagophthalmos,Post ear pain Atx,Puncture bleeding Qd~Qod,1c: 10t,Total 4m Not stated Improved
Rhee DH (2012)31) South Korea F/46 Bell’s palsy 4y Contracture,Synkinesis Atx, PAtx, HM, Physiotherapy 1m ① H-B② P(a)Contracture(b)Synkinesis ① Ⅱ→?② (a) Ⅱ→0 (b) Ⅲ→Ⅱ
F/55 1y Contracture,Synkinesis ① Ⅰ→?② (a) Ⅱ→Ⅰ (b) Ⅲ→Ⅱ
M/59 15y Contracture,Synkinesis Crocodile tears ① Ⅲ→?② (a) Ⅲ→Ⅲ (b) Ⅲ→ⅢCrocodile tears: exist→exist
Lu Q (2012)34) China M/53 Peripheral facial paralysis 2m Lagophthalmos,Stiffness,Post ear pain Atx, Moxa Qd,1c: 10t,Over 2m Not stated Improved
Li H(2012)35) China M/42 Bell’s palsy 7m Stiffness,Asymmetry Atx, Acupoint injection Qd~Qod,1c: 10t,Total 3m Not stated Cured
Fang D (2012)48) China 23 cases(M: 14, F: 9, age: 18~69) Peripheral facial paralysis 6w~20y Facial spasm,Asymmetry,Lagophthalmos Atx, Moxa, HM, Massage,External application therapy Qd,1c: 10t,Total 5w Effective rate 95.65%
Sun F (2012)36) China F/34 Peripheral facial paralysis >6m Lagophthalmos,Asymmetry,Dacryorrhea Fire therapy Qod,Total 20d Not stated Improved
Ni w (2012)38) China 23 cases(M: 10, F: 13, mean age: 49) Bell’s palsy Mean5.8m Dacryorrhea,Lagophthalmos,Paresthesia,Facial spasm Atx, Moxa, Massages 3t/w,Total 8w Portmann score 12.76±2.07→ 16.10±1.97 (p<0.01)
Wang W (2012)32) China 120 cases(M: 89, F: 31, mean age: 40) Bell’s palsy Mean3.3m Lagophthalmos,Dacryorrhea,Asymmetry Atx, HM, Cut therapy HM: tid,Atx: 6~12w,Cut:1t/3~5d,generally no more than 4t)Total c is not stated. Effective rate 98.33%
Wang W (2012)33) China 120 cases(M: 74, F: 46, mean age: 37) Bell’s palsy Mean2.2m Asymmetry,Paresthesia,Contracture Cut therapy 1t/3~5d,generally no more than 4t.Total c is not stated. Effective rate 95.83%
Zhao J (2012)37) China 48 cases(M: 20, F: 28, age: 15~78) Peripheral facial paralysis 2m~3y Paresthesia,Lagophthalmos,Contracture,Facial spasm Atx(fire) Qd~Qod,1c: 5t,Total 4c Effective rate 91.67%
Cho E(2013)39) South Korea F/36 Bell’s palsy 3y Synkinesis,Contracture Jung-An Atx 3m (20) ① Y② P③ SAQ ① 36→39② (a) Ⅱ→Ⅰ (b) Ⅲ→Ⅱ③ 31.1→26.7
F/43 3m Asymmetry,Lagophthalmos,Contracture 1m (10) ① Y② P③ Picture ① 29→33② (a) Ⅰ→0 (b) 0→0
F/42 8m Asymmetry,Lagophthalmos,Contracture,Synkinesis 2m (15) ① 34→37② (a) Ⅱ→Ⅰ (b) Ⅲ→Ⅱ
F/40 18y Asymmetry,Synkinesis 2m (15) ① 39→40② (a) Ⅰ→0 (b) Ⅱ→Ⅰ
Zhao J (2013)41) China 176 cases(M: 73, F: 103, age: 10~75) Bell’s palsy >6m Facial spasm,Contracture,Hearing impairment,Synkinesis Atx, Moxa,Puncture bleeding,Acupoint injection, HM Qd~Qod,1c: 10t,Total 4c Effective rate 82.3%
Han L (2013)40) China 45 cases(M: 28, F: 17, age: 15~64) Peripheral facial paralysis 14w~1y Asymmetry Electro-Atx Qd,1c: 10t,Total c is not stated. Effective rate 95.6%
Su M (2014)42) China 47 cases(M: 32, F: 15, age: 30~70) Bell’s palsy 2m~1y Asymmetry,Paresthesia,Dacryorrhea Atx Qd,1c: 7t,Total c is not stated SFGS(Effective rate) 93.6%
Lee EJ (2015)45) South Korea F/61 Bell’s palsy Not stated Contracture,Crocodile tears,Facial spasm Jung-An Atx 8d (8) H-B(a)Gross(b)Facial nerve (a) Ⅴ→Ⅲ(b) Ⅴ→Ⅲ: 2/8→5/8
Pang Y (2015)43) China 80 cases(M: 48, F: 32, Bell’s palsy 3m~12y Contracture,Facial spasm,Dacryorrhea Atx Qd,1c: 5d,Total 4c H-B(Effective rate) 96.3%
Wang H (2015)44) China 43 cases(M: 28, F: 15, mean age: 55) Peripheral facial paralysis >3m Dacryorrhea Plum blossom needle Qd,1c: 10t,Total 2c Effective rate 86.0%
Heo ES (2016)3) South Korea M/49 Bell’s palsy 1y Asymmetry,Lagophthalmos,Contracture,Synkinesis Jung-An Atx, Infrared, BR mask pack, PAtx, HM, Physiotherapy 8m (17) ① H-B② P③ Picture④ Satisfaction score (Q) ① Ⅲ→Ⅱ② (a) Ⅱ→Ⅰ (b) Ⅲ→Ⅱ④ 5
M/12 1y Asymmetry,Lagophthalmos,Contracture,Synkinesis 5m (18) ① Ⅲ→Ⅱ② (a) Ⅱ→Ⅰ (b) 0→0④ 4
F/63 10m Asymmetry,Synkinesis 1m (12) ① Ⅱ→Ⅰ② (a) Ⅱ→Ⅰ (b) Ⅱ→Ⅰ④ 3
F/57 10m Asymmetry,Contracture 2m (20) ① Ⅲ→Ⅱ② (a) Ⅱ→Ⅰ (b) 0→0④ 4
F/50 8m Asymmetry,Contracture 20d (10) ① Ⅱ→Ⅰ② (a) Ⅱ→Ⅰ (b) 0→0④ 5
Wang J (2018)46) China 42 cases(M: 24, F: 18, age: 26~75) Bell’s palsy 1~3m Asymmetry,Dacryorrhea,Lagophthalmos,Facial spasm Atx, TDP Qd,1c: 12t,Total 2c Effective rate 95.2%
Sx: Symptom, d: day, m: month, y: year, t: time, c: course, Atx: Acupuncture treatment, PAtx: Pharmacopuncture, HM: Herbal medicine, BTX: Botulinum toxin, H-B: House-Brackmann scale, Y: Yanagihara system, SFGS: Sunnybrook facial grading system, P: The Scale of Peitersen, (Q): Questionnaire, SAQ: Synkinesis Assessment Questionnaire, Facial nerve: Facial Nerve Grade Systems by Brackmann.