| Firstauthor(year) | Subjects | Intervention | ResultsT/C | Adverse effect | ||
|---|---|---|---|---|---|---|
| N(T/C)* | Mean age | Mean DI†(year) | ||||
| Zhang(2009) | 104(52/52) | T:23.12±12.54C:22.92±11.85 | T:(3.68+4.32)C:(3.86+4.23) | T:Herbal medicine with CC:Vitamin capsule | 1) Cured 32/16(61.54%/30.77%)2) Improve 14/18(26.92%/34.62%)3) Invalid 6/18(11.54%/34.62%)4) Total efficacy rate 88.46%/65.38% | Not mentioned |
| Ma(2010) | 200(100/100) | 36(15~61) | 2.9(0.1~10) | T:Herbal medicine with CC:Vitamin capsule, hasinide solution, glucose chlorhexidine ointment | 1) 2weeks efficiency 41%/10%2) 4weeks efficiency 73%/35%3) 6weeks efficiency 89.5%/66.4%4) Total efficiency 89.5%/66.4% | 8 cases |
| Li(2012) | 100(50/50) | T:32(20~45)C:31(21~46) | T:1.2(0.2~4)C:1.3(0.3~3.8) | T:Herbal medicineC:Cetirizine, multivitamin B | 1) Cured 35/242) Significant effect 9/73) Improvement 5/114) Invalid 1/85) Efficacy 88%/62%6) Cure rate 70%/48% | No adverse effect |
| Ma(2015) | 82(42/40) | T:32.6(19~45)C:34.3(18~47) | T:0.84(0.3~5)C:0.76(0.3~6) | T:Herbal medicine with CC:0.1% Tacrolimus ointment | -Efficacy1) Cured 30/25(71.4%/62.5%)2) Significant effect 6/4(14.3%/10.0%)3) Improved 5/4(11.9%/10%)4) Invalid 1/7(2.5%/17.5%)5) Total efficacy 41/38(97.5%/82.5%)-Recurrence rate1) 2weeks 2/5(6.7%/20.0%)2) 4weeks 4/12(13.3%/48.0%) | T:8 cases C:9 cases |